Access to second-line drug susceptibility testing results among patients with Rifampicin resistant tuberculosis after introduction of the Hain Line Probe Assay in Southern provinces, Zimbabwe
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چکیده
منابع مشابه
Resistance to Second-Line Antituberculosis Drugs and Delay in Drug Susceptibility Testing among Multidrug-Resistant Tuberculosis Patients in Shanghai
Introduction. Second-line antituberculosis drugs (SLDs) are used for treating multidrug-resistant tuberculosis (MDR-TB). Prolonged delays before confirming MDR-TB with drug susceptibility testing (DST) could result in transmission of drug-resistant strains and inappropriate use of SLDs, thereby increasing the risk of resistance to SLDs. This study investigated the diagnostic delay in DST and pr...
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The potentially pathogenic Non-Tuberculosis Mycobacteria (NTM) are emerging nowadays which result in pulmonary and non-pulmonary infections in human. This group of bacteria consists of at least 200 different species. While the pulmonary disease is the most common form of NTM infections, NTM can cause diffused infections as well as extrapulmonary infections in every organ, such as bone marrow, s...
متن کاملRapid Detection of Multi Drug Resistance among Multi Drug Resistant Tuberculosis Suspects Using Line Probe Assay
Objective: GenoType MTBDRplus line probe assay (LPA) is developed for performing drug susceptibility testing (DST) for Rifampicin (RIF) and isoniazid in sputum specimens from smear-positive pulmonary tuberculosis (TB) patients and revised national TB control Programme (RNTCP) has endorsed LPA for the diagnosis of multi drug resistant TB (MDR-TB). This study was conducted to assess the potential...
متن کاملSecond-line anti-tuberculosis drug concentrations for susceptibility testing in the MODS assay.
Multidrug-resistant tuberculosis (TB) threatens TB control worldwide. The microscopic observation drug susceptibility (MODS) assay is a low-cost, high-performance TB diagnostic tool for rapid liquid culture and direct isoniazid and rifampicin drug susceptibility testing (DST). The objective of this study was to explore the potential for extending the MODS assay to rapid second-line DST and to i...
متن کاملAssociation of drug susceptibility testing results for first- and second-line drugs with treatment outcomes in patients with multidrug-resistant and extensively drug-resistant tuberculosis.
TO THE EDITOR—We read the metaanalysis by Bastos et al recently published in Clinical Infectious Diseases [1]. Because of our interest in the association of drug susceptibility testing (DST) results for firstand second-line drugs with treatment outcomes in patients with multidrugresistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis, we carefully read the entire article....
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2019
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2019.02.007